Learn about St Johns Wort
Your source for clear, up-to-date information on St. John's Wort (Hypericum perforatum) and the dietary supplements made from it — what it is, how it affects mood, what the research shows, and how to pick a quality product.
St. John's Wort is one of the most widely studied herbal remedies for low mood. Use the guides below to learn how it works, weigh it against prescription options, and choose a supplement that actually contains what it claims.
The Basics
What the plant is, the active compounds it contains, how it affects mood, and its long history of use.
Learn the basics →Depression & Anxiety
How St. John's Wort works on brain chemistry and how it compares to prescription antidepressants.
How it works →The Science
An overview of the clinical research, a look at key trials, and what separates a good study from a weak one.
Review the research →Choosing a Brand
What to look for on the label, red flags to avoid, and what standardized-extract percentages mean.
Choose wisely →